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Welcome to the HADDOCK 2.4 webserver!

HADDOCK (High Ambiguity Driven protein-protein DOCKing) is an information-driven flexible docking approach for the modeling of biomolecular complexes. HADDOCK distinguishes itself from ab-initio docking methods in the fact that it encodes information from identified or predicted protein interfaces in ambiguous interaction restraints (AIRs) to drive the docking process. HADDOCK can deal with a large class of modeling problems including protein-protein, protein-nucleic acids and protein-ligand complexes.
More information about HADDOCK2.4 can be found on the HADDOCK2.2 website
Read also what an independent review by Moreira et al. has to say about our software...

HADDOCK is one of the flagship software in the EU H2020 BioExcel Center of Excellence for Biomolecular Research.
The access of HADDOCK web server is free for non-profit users upon registration.

Registration: To use the HADDOCK docking server you must have registered for an account. If you do not have a account yet you can register here

Submission: Try now our new submission interface here !!!

G.C.P van Zundert, J.P.G.L.M. Rodrigues, M. Trellet, C. Schmitz, P.L. Kastritis, E. Karaca, A.S.J. Melquiond, M. van Dijk, S.J. de Vries and (2016). "The HADDOCK2.2 webserver: User-friendly integrative modeling of biomolecular complexes."
J. Mol. Biol., 428, 720-725 (2015).

The default HADDOCK settings used by the server can be found here
A list of modified amino acids supported by HADDOCK can be found here